Most phenethylamines act as either central nervous system stimulants, or as hallucinogens. Phenethylamine increases a chemical in the brain called serotonin. Synthetic Drug Abuse, Understanding the Dangers of, https://www.unodc.org/LSS/SubstanceGroup/Details/275dd468-75a3-4609-9e96-cc5a2f0da467, http://www.health.ny.gov/regulations/recently_adopted/docs/2013-01-02_synthetic_phenethylamines_and_synthetic_cannabinoids_prohibited.pdf, Narconon International Science Advisory Board.
It is popular at dance venues and music festivals as it gives one a feeling of artificial closeness to other people. Increased stress response and beta-phenylethylamine in MAOB-deficient mice. [9]King’s College London. It is also a central nervous system depressant which may mean that it causes a person to stop breathing or slows the heart to a dangerous or even fatal rate. and Bai, Y.M. View abstract. View abstract. Institute of psychiatry, Psychonaut Web Mapping Research Group, ‘Bromo-Dragonfly report’, London UK, 2009, (http://194.83.136.209/documents/reports/Bromodragonfly. 1987;92(2):243-55. Do not take phenethylamine if you are taking dextromethorphan (Robitussin DM, and others). It’s found in low quantities compared to other amino acids.
2C-T-7: Vomiting, headaches, confusion, delirium, high blood pressure. View abstract. [1]The phenethylamines also include ring substituted substances such as the ‘2C series’, ring substituted amphetamines such as the ‘D series’ (e.g.DOI, DOC), benzodifurans (e.g.
Ingestion is the most common route of administration of phenethylamines. Phenylethlyamine modulation of affect: therapeutic and diagnostic implications. 2009;9(10):2695-710. View abstract. View abstract. Trends Pharmacol Sci. Street names for some phenethylamines include ‘Europa’ for 2C-E; ‘4-FMP’, ‘para-fluoroamphetamine’, ‘RDJ’ for 4-FA; and ‘4-MMA’, ‘Methyl-MA’ for PMMA.
This can result in convulsions, coma, kidney failure and death. Whereas some phenethylamines such as 2C-B, brolamphetamine (DOB), STP/DOM, MDE, 4-MTA, are listed in Schedules I and II of the 1971 Convention, most of the new substances such as the 2C series, the D-Series and ‘others’ such as PMMA are not under international control.
The ‘2C’ series differs from the ‘D’ series only by a slight modification in the chemical structure, and their psychoactive effects have been reported to be dose dependant, ranging from mere stimulant effect at lower doses, with hallucinogenic and entactogenic effects at higher doses.[3]. Special Precautions & Warnings: have reported severe hyperthermia following the use of these substances. Grimsby J, Toth M, Chen K, et al. 2001;35(5):342-3. View abstract. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Narconon and the Narconon logo are trademarks and service marks owned by the Association for Better Living and Education International and are used with its permission. Smith T. Phenethylamine and related compounds in plants. Other phenethylamines such as PMMA, first synthesized in 1938,[6] are also sold in the drug market as a substitute for ‘ecstasy’. 2008;325(2):617-28.
Phenylethylamine — also sometimes called PEA, phenethylamine HCL or beta phenylethylamine — is an organic compound that’s found in the human body and also taken by mouth for several purposes. Phenethylamines are usually available in form of pills, but FLY compounds are commonly sold in powder form, while oral doses (on a slip of blotter paper) are usually available for ‘D substances’. View abstract. These are strong stimulants and hallucinogens. [5] Benzodifurans, such as ‘FLY’ (tetrahydrobenzodifuranyl) and ‘Dragonfly’ (benzodifuranyl aminoalkanes) are potent hallucinogens. No To Hattatsu.
Figueiredo T, Viegas R, Lara L, et al.
Crit Rev Food Sci Nutr.
pdf; accessed in: September 2012); Wood, D.M., Looker, J.J., Shaikh, [10]Andreasen, M.F., Telving, R., Birkler, R., Schumacher, B. and Johannsen, M., ‘A fatal poisoning involving Bromo-Dragonfly’, Annales de Toxicologie Analitique, 20 (1), 1-55; Personne, M., Hulten, P., ‘Bromo-Dragonfly, a life threatening designer drug’, Journal: Clinical Toxicology, 2008, 46, 379-80, [11]Miyajima, M., Matsumoto, T and Ito, S., ‘2C-T-4 intoxication: acute psychosis caused by a designer drug’, Journal: Psychiatry and Clinical Neurosciences, 2008, 62, 243, [12]Curtis, B., Kemp, P., Harty, L., Choi, C. and Christensen, D., ‘Postmortem identification and quantitation of 2,5-dimethoxy-4-n-propylthiophenethylamine using GC-MSD and GC-NPD’, Journal of Analytical Toxicology, 2003, 27, 493-98, [13]Ling, L.H., Marchant, C., Buckley, N. A., Prior, M., Irvine, R.J., ‘Poisoning with the recreational drug paramethoxyamphetamine (‘ death ’)’, Medical Journal of Australia, 2001, 174, 453-55; De Letter, E.A., Coopman, V.A., Cordonnier, J.A. Taking phenethylamine along with dextromethorphan (Robitussin DM, others) might cause too much serotonin in the brain and can result in serious side effects including heart problems, shivering, and anxiety. Just imagine a young person suffering from symptoms like these when all he wanted was to go to a party and have a good time: With some of these drugs, a person may go suffer an intense rigidity of muscles. View abstract. [1]Hill, SL., Thomas, S.H., ‘Clinical toxicology of newer recreationaldrugs’, Journal: Clinical Toxicology, 2011, 49(8), 705-19, [2]Alexander Shulgin research institute, ‘Alexander ‘Sasha’ Shulgin’ (http://www.shulginresearch.org/home/about/alexander-sasha-shulgin/), [3] Huang, H.H.
Miller G. The emerging role of trace amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity.
Taking phenethylamine along with desipramine (Norpramin) might increase the levels and the effects of phenethylamine. DOC, DOI) and the ‘2C series’ (e.g. PMA and PMMA are known to have a particularly high toxicity but there is no data available on fatalities associated with their use. In general, stimulants speed up the heart and increase the blood pressure. A renaissance in trace amines inspired by a novel GPCR family. Neurochem Res. View abstract. Minchin RF, Barber HE, Ilett KF. If there are any undiagnosed heart problems, this stress can be fatal. Phenethylamine increases a brain chemical called serotonin. Nakamura M, Ishii A, Nakahara D. Characterization of beta-phenyltheylamine-induced monoamine release in rat nucleus accumbens: a microdialysis study.
Phenethylamine works similar to the drug amphetamine, and may cause similar side effects. Stimulants mediate the actions of dopamine, norepinephrine and/or serotonin, mimicking the effects of traditional drugs such as cocaine, amphetamine, methamphetamine, and ecstasy. One drug from this class has been widely used in Europe and the US for several years - Ecstasy, also known as … View abstract. Mantegazza P, Riva M. Amphetamine-like activity of beta-phenethylamine after a monoamine oxidase inhibitor in vivo. View abstract. Taking phenethylamine along with these medications for depression might increase serotonin too much and cause serious side effects including heart problems, shivering, and anxiety. ©2018 WebMD, Inc. All rights reserved. Surgery: Phenethylamine might affect the central nervous system. Miley (MDA or 3,4-methylenedioyamphetamine), 2C-B: Heart disturbances, confusion, dehydration (which can lead to overheating and organ failure), 2C-I: Seizures, confusion, kidney failure, skyrocketing blood pressure. Beck O, Helander A, Karlson-Stiber C, et al. Taking phenethylamine along with tramadol (Ultram) might cause too much serotonin in the brain and might result in side effects including confusion, shivering, stiff muscles, and others. 2012;135(3):2005-11. Ann Neurol. 2C-T: Panic attacks, vomiting, delirium, amnesia.
Phenethylamine increases a chemical in the brain called serotonin. People who don't make enough phenethylamine naturally may be helped by taking phenethylamine as a supplement. View abstract.
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