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This course is an elective course for 2nd year Cancer Biology Students on a range of cancer-related topics. We will explore mechanisms that underlie replication and division, particularly control mechanism that maintain genome integrity and are critical to prevent disease. Subsequently, both "historical" and more recent papers in the field of cancer metabolism are reviewed with individual faculty experts in each chosen area. The research efforts of these extraordinary scientists are diverse in their focus, experimental system, methodology, and represent the leading edge of basic and translational biomedical science. The Program in Microbiology, Virology, and Parasitology provides students an opportunity to undertake concentrated study in the molecular and cellular biology of viral and bacterial pathogenesis and parasitology. Prerequisite: Permission needed from Department, Course offered summer, fall and spring terms, CAMB 703 The ECM, adhesion receptor signaling, and translational biomechanics. The organizers, along with faculty from the School of Medicine, the Wistar Institute and CHOP, with expertise in the corresponding areas provide lectures for the course. There are required readings to provide the student context and background for the diverse lectures. Classes will run from 10am to 11:30AM on Mondays and Wednesdays in Johnson 207. The PDF will include all information unique to this page. Within this integrated program are six discipline areas: Cancer Biology (CB); Cell Biology, Physiology, and Metabolism (CPM); Developmental, Stem Cell, and Regenerative Biology (DSRB); Genetics and Epigenetics (G&E); Gene Therapy and Vaccines (GTV); and Microbiology, Virology, and Parasitology (MVP). Must have completed first-year CAMB courses to enroll. This course is designed for graduate students but advanced undergraduates with a strong background in genetics are also welcome. The goal of the course is to provide students with a view of the cancer cell that integrates both cell autonomous and non-cell autonomous signals and to use this information to consider how to successfully treat cancer. Students will be graded based on their introductory presentation and active participation in the paper discussions. We will discuss how these topics can inform the study of cell biology, physiology and disease. CAMB 504 Topics in Gene Therapy and Vaccines, CAMB 505 Topics in Cell and Molecular Biology, CAMB 506 Topics in Microbiology, Virology and Parasitology. student may enter either term. This is a year-long course for the incoming CAMB-MVP students and others wishing to gain a broad overview of pathogens and their interactions with hosts. The goal is to familiarize students with the latest cutting-edge genomics tools and cover solutions to major experimental and computational challenges in the investigation of genome-wide epigenetic data sets. 3451 Walnut Street University of Pennsylvania Philadelphia, PA 19104 Mon, Wed, Thurs, Fri: 9am – 5pm Tue: 10am – 5pm Sat, Sun: Closed

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